Older hospital patient being reassured by a clinician

Acute confusion is a medical warning sign

Delirium is sudden brain failure until proven otherwise.

Delirium is an abrupt, fluctuating change in attention, awareness and thinking. It is common in older adults, after surgery, during severe infection, with medication toxicity or withdrawal, and in people living with dementia.

First hour mindset

Do the bedside basics while looking for the trigger.

  1. Confirm acute change: compare with baseline and collateral history.
  2. Stabilize ABCDE: oxygen, glucose, temperature, pain, hydration, safety.
  3. Screen delirium: 4AT on wards; CAM-ICU or ICDSC in ICU/recovery.
  4. Find reversible causes: infection, sepsis, drugs, withdrawal, metabolic, neurologic.
  5. Protect the brain: orientation, sleep, glasses/hearing aids, mobility, family presence.
11-25%

Approximate delirium prevalence among adults 65+ at hospital admission; community prevalence is much lower.

AAFP 2023
10-50%

Reported postoperative incidence range in older adults, varying by operation, acuity and assessment frequency.

POQI-6 consensus
31%

Pooled adult ICU prevalence in a systematic review and meta-analysis; ventilated and high-severity groups may be higher.

Krewulak 2018
Often missed

Hypoactive delirium can look like sleepiness, withdrawal, depression or "just dementia".

NICE CG103

Language safety

Aboriginal and Torres Strait Islander languages need interpreters, not guesswork.

Many Aboriginal and Torres Strait Islander patients speak English as a second, third or fourth language. For delirium, pain, consent, discharge planning and medicines, machine translation is not reliable enough. Use a professional Indigenous language interpreter whenever comprehension is uncertain.

Northern Territory

NT Government lists more than 100 Aboriginal languages and dialects. Widely spoken languages include Kriol, Yolngu Matha, Warlpiri, Pitjantjatjara, Murrinh-Patha, Anindilyakwa, Arrernte/Arrarnta, Kunwinjku, Burarra, Tiwi, Luritja/Pintupi, Gurindji, Maung, Alyawarr/Anmatyerr and Warumungu.

NT Aboriginal Interpreter Service language guide

Western Australia

Aboriginal Interpreting WA is the specialist Aboriginal language interpreting service across WA and works in more than 40 WA Aboriginal languages. WA Health resources also list Aboriginal English, Kriol, Kukatja, Martu Wangka/Wangkajunga, Miriwoong and other local language needs.

Aboriginal Interpreting WA

Queensland

Queensland includes many Aboriginal languages, Torres Strait Islander languages and Indigenous sign languages. Queensland Indigenous Interpreting Service supports professional interpreting across Queensland, including the Torres Strait Islands.

Queensland Indigenous Interpreting Service

Clinical prompt

Ask: "What language do you speak at home?" and "Would you like an interpreter?" Do not use family for high-stakes interpreting unless there is an immediate emergency and no interpreter is available. Record the preferred language and interpreter need in handover.

National Indigenous Australians Agency interpreter services

Aotearoa New Zealand

Te reo Māori is included in the language selector for whole-page translation. For clinical decisions, consent, medicines and discharge planning, use a qualified interpreter where communication is uncertain and include whānau according to the patient's wishes.

New Zealand Ministry of Health Māori health resources

Plain patient and family guide

What families can say, ask and watch for

Say this to staff

  • This is not normal for them.
  • They were last normal at this time.
  • They usually know these people, places and routines.
  • These medicines, alcohol use, falls, infections or pain changes are new.

Ask this

  • Could this be delirium?
  • Have oxygen, glucose, infection, pain, medicines, bladder and bowels been checked?
  • Can we bring glasses, hearing aids, dentures, familiar objects and family support?
  • What should make us call urgently tonight?

Watch at home or care home

  • New confusion, sleepiness, fear, agitation, hallucinations or falls.
  • Not eating or drinking, fever, cough, urine symptoms, constipation or pain.
  • New tablets, missed tablets, sleeping tablets, opioid pain medicines or withdrawal.
  • Stroke signs, seizure, severe drowsiness, breathing trouble or unsafe behavior need urgent help.

Patient and family section

What families notice first

Delirium usually develops over hours to days and changes during the day. The person may be alert one moment and drowsy, frightened, suspicious, restless or unusually quiet the next. A family member's description of "not their normal self" is often the clue that starts the diagnosis.

Urgent care is needed

New confusion, marked drowsiness, agitation, fever, shortness of breath, chest pain, seizure, weakness on one side, head injury, overdose, or alcohol/benzodiazepine withdrawal symptoms should be treated as urgent until a clinician has assessed the cause.

Symptoms and signs

  • Reduced attention: cannot follow conversation, distractible, loses track.
  • Fluctuation: worse at night, after medications, during fever or dehydration.
  • Disorganized thinking: rambling, odd beliefs, misreading the environment.
  • Altered arousal: hyperactive, hypoactive, or mixed within the same day.
  • Sleep-wake disruption, nightmares, hallucinations or misperceptions.
  • New incontinence, falls, poor intake, reduced mobility or picking at lines.

Types and contexts

Delirium is one syndrome with many doors in.

Most patients have both vulnerability factors and one or more acute triggers. The practical question is not "which single cause?" but "which dangerous, reversible contributors are present today?"

Postoperative delirium

Common after major surgery, hip fracture, cardiac surgery and emergency operations. Risk rises with age, dementia, frailty, sensory impairment, infection, pain, sleep disruption, blood loss, ICU stay, urinary catheters, and deliriogenic medicines.

Drug-induced delirium

Anticholinergics, sedatives, opioids, corticosteroids, dopamine agonists, polypharmacy, renal failure with drug accumulation, and interactions are frequent causes. Medication review is a diagnostic test.

Delirium with dementia

Dementia is a major risk factor, but delirium is a new change from baseline. If uncertain, manage the delirium first, then reassess cognition after recovery.

Infection and sepsis

Pneumonia, urinary infection, cellulitis, abdominal sepsis, line infection, meningitis/encephalitis and COVID-like respiratory infections can present mainly as confusion in older adults.

ICU delirium

Ventilation, hypoxia, shock, sedatives, immobilization, sleep disruption, pain and critical illness inflammation make ICU delirium common and prognostically important.

Withdrawal states

Alcohol, benzodiazepine, barbiturate and some drug withdrawal syndromes can be life-threatening and need protocolized treatment, monitoring and thiamine where alcohol misuse or malnutrition is possible.

Clinical team reviewing a chest X-ray

Infection is common, but not the only answer

Pneumonia, UTI and sepsis checks sit inside a broader delirium workup.

A positive urine test alone does not explain everything. The question is whether there is a true infection, organ dysfunction, hypoxia, drug effect, withdrawal, stroke, seizure, pain, retention or another concurrent trigger.

Clinician section

Diagnostic frame: acute attention failure plus a cause.

Use collateral history, baseline cognition/function, medication timing, observations and a structured bedside tool. Treat delirium as a medical emergency while avoiding over-investigation that ignores the bedside story.

Core diagnostic features

  • Acute onset and fluctuating course.
  • Inattention is central: months backwards, digit span, inability to track conversation.
  • Disorganized thinking or altered level of consciousness.
  • Evidence that the disturbance is caused by medical illness, substance, toxin or multiple causes.

Validated tools

  • 4AT: rapid ward, emergency and long-term-care screening with a 0-12 score.
  • CAM: classic diagnostic algorithm when staff are trained; not a severity score.
  • CAM-ICU or ICDSC: ICU and post-anaesthesia recovery settings.
  • Severity tracking: repeat screens, arousal scale, pain and function measures.

Phenotypes

  • Hyperactive: agitation, pulling lines, fear, hallucinations.
  • Hypoactive: quiet, slowed, withdrawn, reduced intake; high miss rate.
  • Mixed: switches between restless and drowsy, often within hours.

Fillable bedside tools

Delirium scoring and diagnostic algorithms

These calculators are educational implementations of commonly used bedside tools. They support, but do not replace, trained clinical judgement, local policy, collateral history and urgent investigation of organic causes.

Ward / ED / aged care

4AT

A rapid four-item screen. It gives a numeric score, but a positive result still requires clinical diagnosis and a search for the precipitating cause.

4AT score 0 / 12

0: delirium or moderate-severe cognitive impairment is unlikely, but not excluded if clinical concern remains.

  • 1-3 suggests possible cognitive impairment without clear delirium.
  • 4 or more suggests possible delirium, with or without cognitive impairment.
  • 4AT is designed to still score patients who are too drowsy or inattentive for cognitive tests.
Trained ward / ED use

CAM short algorithm

CAM is a diagnostic algorithm, not a severity scale. It is positive when features 1 and 2 are present, plus either feature 3 or feature 4.

CAM result Negative

CAM negative by the short algorithm. If clinical concern remains, repeat assessment and search for causes.

  • Feature 1 needs a change from baseline or fluctuation, usually from collateral history or serial observation.
  • Feature 2 means attention is impaired: distractible, cannot track questions, poor digit span or months backwards.
  • CAM positivity does not grade severity; track severity separately with repeated assessments, arousal and function.
ICU / PACU

CAM-ICU

CAM-ICU adapts the CAM for critically ill or non-verbal patients. Assess arousal first. If the patient is not arousable enough to participate, document unable to assess rather than calling it negative.

CAM-ICU result Negative

CAM-ICU negative by algorithm. Feature 3 is generated from RASS: any RASS other than 0 counts as altered level of consciousness.

  • Feature 3 is altered consciousness: RASS not equal to 0.
  • Positive CAM-ICU: feature 1 plus feature 2 plus feature 3 or 4.
  • RASS -4 or -5 is generally unable to assess for CAM-ICU.
ICU shift screen

ICDSC

The Intensive Care Delirium Screening Checklist scores eight features observed during the shift or preceding 8-24 hours. It is useful for repeated ICU screening and trend monitoring.

ICDSC score 0 / 8

0: no delirium features documented during the observation period.

  • 1-3 is often described as subsyndromal or possible delirium and should prompt reassessment.
  • 4 or more is a positive ICDSC screen for delirium in many ICU protocols.
  • Use alongside arousal assessment and clinical review of sedation, ventilation, sepsis and neurologic causes.
Nursing observation

Nu-DESC

The Nursing Delirium Screening Scale is a rapid observation tool scored during a nursing shift. It tracks five visible delirium behaviors, each rated absent, mild or marked.

Nu-DESC score 0 / 10

0: no Nu-DESC delirium behaviors documented during the observation period.

  • 2 or more is commonly used as a positive Nu-DESC delirium screen.
  • 1 may still justify repeat screening or adding an attention test, especially if concern is high.
  • Nu-DESC is observational; it should be paired with baseline history and cause-finding.

Order of testing

A practical delirium investigation sequence

Adapt to acuity, local policy and the patient's goals of care. The safest order is: identify immediate danger, prove the syndrome, then test for common and dangerous causes in parallel.

1

Immediate bedside checks

Airway, breathing, circulation, disability, exposure. Vitals, oxygen saturation, temperature, capillary glucose, pain, hydration, urinary retention/constipation, falls or head injury, medication timing, alcohol/drug history, and current safety risk.

2

Mental status and baseline

Collateral history, baseline cognition and function, 4AT/CAM or CAM-ICU/ICDSC, arousal level, focal neurology, meningism, seizure activity, psychosis, suicidality, capacity and communication barriers.

3

Core tests for most acute presentations

CBC, electrolytes, renal/liver function, calcium, magnesium if relevant, glucose, CRP or other inflammatory marker by local practice, ECG before QT-prolonging drugs, urinalysis with culture only when symptoms/signs support UTI, medication levels where relevant.

4

Infection, hypoxia and sepsis screen

Chest exam and chest X-ray when respiratory signs, hypoxia or fever are present; blood cultures and lactate when sepsis is suspected; focused cultures from likely sites; review catheters, wounds, lines, abdomen, skin and meningitis/encephalitis features.

5

Medication, toxin and withdrawal review

Anticholinergic burden, sedatives, opioids, steroids, dopamine agonists, new antibiotics, recreational drugs, alcohol cessation, benzodiazepine withdrawal, renal dosing, interactions and recent anaesthetic exposure.

6

Neurologic escalation

Head CT or MRI when focal deficit, new seizure, reduced consciousness without explanation, head trauma, anticoagulation with fall, severe headache, suspected stroke/bleed, cancer, immunosuppression or failure to improve. EEG if non-convulsive seizure/status is plausible. Lumbar puncture if CNS infection/inflammation is suspected and imaging/bleeding risk are addressed.

7

Endocrine, nutritional and psychiatric contributors

TSH, B12, cortisol, ammonia, ABG/VBG, toxicology or other tests when the history fits. Depression, mania, psychosis and trauma can coexist, but a new fluctuating attention deficit should remain delirium until medical causes are treated.

Step-by-step management

Simple flow charts for acute and postoperative delirium

These are bedside logic maps. They do not replace local stroke, sepsis, shock, trauma, toxicology or surgical escalation pathways; they make sure those serious organic causes are actively excluded before settling into routine delirium care.

Emergency

New acute confusion or agitation

  1. Recognize acute change

    Collateral baseline, onset over hours/days, fluctuating attention or arousal.

  2. Immediate danger screen

    ABCDE, vitals, oxygen saturation, glucose, temperature, pain, trauma, overdose, withdrawal risk.

  3. Red flags present?

    Stroke signs, seizure/status, meningism, head injury, shock, sepsis, hypoxia, hypoglycemia, severe intoxication.

  4. If yes: activate emergency pathway

    Stroke/sepsis/shock/trauma/toxicology care, senior review, imaging or resuscitation as indicated.

  5. If no or after stabilization: confirm delirium

    4AT or CAM; CAM-ICU/ICDSC if critically ill, ventilated or in recovery.

  6. Find common reversible triggers

    Medication burden, infection evidence, retention/constipation, dehydration, electrolytes, renal/liver failure, pain, sleep loss.

  7. Start brain-protective care

    Reorientation, calm observation, sensory aids, family presence, mobilization, hydration, sleep, remove unnecessary tethers.

  8. Reassess frequently

    Repeat vitals and mental status; if worsening or not improving, revisit red flags and broaden tests.

Post-op

Confusion after surgery or anaesthesia

  1. Do not dismiss as anaesthetic only

    Check baseline cognition, operation, anaesthetic record, fluids, blood loss, analgesia and timing.

  2. PACU or ward safety check

    Airway, oxygenation, ventilation, BP, pulse, temperature, glucose, pain, bleeding, urine output.

  3. Surgical or neurologic emergency?

    Shock, sepsis, hypoxia, hemorrhage, stroke signs, seizure, malignant hyperthermia, PE, compartment or uncontrolled pain.

  4. If yes: escalate immediately

    Surgeon/anaesthetist/senior clinician review, resuscitation, imaging, labs and source control as indicated.

  5. If stabilized: screen for delirium

    CAM-ICU/ICDSC in PACU or ICU; 4AT/CAM on the ward; document arousal and fluctuation.

  6. Remove postoperative triggers

    Over-sedation, anticholinergics, benzodiazepines, excessive opioids, urinary catheter, retention, constipation, dehydration.

  7. Recovery bundle

    Analgesia without oversedation, early mobilization, nutrition, glasses/hearing aids, daylight, sleep protection, family orientation.

  8. Plan discharge and prevention

    Explain the episode, deprescribe where possible, flag future delirium risk and arrange cognition/function follow-up.

Treatment after stabilization

Once dangerous and reversible causes are treated, manage the delirium itself.

Delirium care is active treatment, not watchful waiting. The aim is to reduce distress, shorten exposure to triggers, prevent complications, maintain function and communicate clearly until the brain recovers.

1. Continue cause control

Recheck the original trigger and look for second hits: sepsis response, oxygenation, glucose, hydration, pain, retention, constipation, medication accumulation, sleep loss, bleeding, stroke/seizure red flags and withdrawal. Delirium often has more than one cause.

2. Build a calm brain environment

Daylight, clock/calendar, quiet nights, familiar objects, glasses/hearing aids, dentures, interpreter, repeated orientation and family presence. Explain every intervention before touching or moving the person.

3. Mobilize and detether

Sit out of bed, walk early when safe, remove unnecessary cannulas, catheters and monitors, avoid restraints where possible, prevent pressure injury and falls, and keep nutrition/hydration visible.

4. Treat distress without oversedation

Use verbal and non-verbal de-escalation first. Check pain, fear, toileting, hunger, breathlessness and sensory barriers. Hypoactive delirium may still involve frightening hallucinations or delusions.

5. Use drugs only for safety or severe distress

Antipsychotics do not fix delirium. Consider short-term use only when the person is severely distressed or risks harm and de-escalation is ineffective or inappropriate. Start low, review daily and stop as soon as possible.

6. Avoid making delirium last longer

Avoid benzodiazepines unless specifically indicated, such as alcohol/benzodiazepine withdrawal, seizures or catatonia. Avoid new anticholinergics, sedating antihistamines, unnecessary hypnotics and polypharmacy.

Daily delirium ward round

  1. What is the baseline, and is attention/arousal better, worse or fluctuating today?
  2. Which cause has been treated, and what second cause could still be active?
  3. Which medication can be stopped, reduced or dose-adjusted for renal/liver function?
  4. What is the mobility, sleep, hydration, pain, bowel and bladder plan for the next 24 hours?
  5. Who has updated family/care home, and what recovery/follow-up plan is documented?

Discharge and recovery

Document delirium clearly. Warn that recovery can take days to months, and that future admissions or operations carry higher risk. Arrange medication review, cognitive reassessment after recovery, mobility/function follow-up and care-home prevention instructions.

Drugs and alcohol

Medication review is both prevention and treatment.

Delirium can be caused by starting, stopping, accumulating or combining medicines. In older adults, anticholinergic load and sedative burden matter as much as any single named drug.

Medication vials and tablets representing delirium risk

Common drug contributors

  • Anticholinergics: atropine-like effects, bladder antimuscarinics, tricyclics, antihistamines.
  • Benzodiazepines, Z-drugs, barbiturates and sedating antihistamines.
  • Opioids, especially high dose, renal accumulation, or combined sedatives.
  • Corticosteroids, dopamine agonists, anticonvulsants, lithium, digoxin toxicity.
  • Some antimicrobials and antivirals, especially with renal impairment or CNS vulnerability.

Reversal and specific antidotes

  • Glucose for hypoglycemia; treat immediately.
  • Naloxone for clinically significant opioid toxicity with respiratory depression.
  • Thiamine when alcohol misuse, malnutrition or Wernicke risk is possible.
  • Flumazenil only in carefully selected benzodiazepine toxicity; seizure risk can be serious.
  • Physostigmine is a toxicology/critical-care decision for severe anticholinergic toxicity, not routine delirium treatment.

Usually avoid or minimize

  • New sedatives for "sleep" during delirium.
  • Antipsychotics for prevention or to hasten delirium resolution.
  • Benzodiazepines unless treating alcohol/benzodiazepine withdrawal, seizures, catatonia, or another specific indication.
  • Physical restraints when observation, family presence, de-escalation and environmental changes can reduce risk.
Postoperative recovery room with patient under observation

Postoperative delirium

Prevent before the operation, detect early after it.

Preoperative risk recognition, sensory aids, medication simplification, pain control, hydration, avoiding unnecessary tethers, early mobilization and sleep protection are the backbone. After surgery, do not assume confusion is "just anaesthetic"; assess for hypoxia, sepsis, bleeding, retention, pain, stroke and drugs.

High-risk settings

Hip fracture, pre-surgical screening and home detection

Hip fracture, frailty, dementia and preoperative cognitive impairment sharply increase delirium risk. The practical response is early recognition, prevention bundles, and clear communication between family, care homes, general practice, ambulance services and hospitals.

Hip fracture

Treat every older hip-fracture patient as high risk. Start orientation, hydration, analgesia without oversedation, oxygenation, bowel/bladder care, medication review, early orthogeriatric input and mobilization planning as soon as feasible.

Pre-surgical cognitive screen

Ask about baseline memory, function, prior delirium and care-home residence. Consider Mini-Cog, MoCA, AMT4/4AT or local geriatric-surgery screening; a low screen should trigger prevention planning, not automatic cancellation.

Nursing-home and care-home patients

Avoid reflex hospital transfer when the person is stable and assessment can be done safely in place. Send baseline cognition, medication changes, observations, hydration/intake, falls, infection signs and family concerns with any escalation.

When hospital is needed

New focal weakness, seizure, head injury, severe pain, hypoxia, shock, sepsis features, chest pain, dangerous agitation, overdose, withdrawal, inability to maintain hydration, or unsafe care at home needs urgent clinical escalation.

Family and care-home tool

Adapted home delirium check

This is a CHAMEOS+-inspired checklist, adapted for this website because I could not verify a canonical published CHAMEOS+ version. Use it as a practical prompt to detect new or worsening delirium and to find reversible contributors; use Family CAM or local tools when a validated family screen is needed.

0 areas flagged

No home-check areas selected. Keep watching for sudden change, especially in dementia, infection, dehydration, after falls or after medication changes.

Prediction and prevention

The best delirium treatment is a prevention plan started early.

Risk tools differ by setting, but the same prevention domains repeatedly appear in guidelines and trials: orientation, mobility, hydration, nutrition, sleep, sensory aids, pain control, medication review and early treatment of acute illness.

Bedside risk helper

Select risk factors present now. This is not a diagnostic score; it helps prompt prevention.

No factors selected 0

Prevention bundle

Action plans

What to do by situation

Family or carer plan

  1. Tell staff the person's normal memory, mobility, personality, hearing and vision.
  2. Report the time course: exactly when confusion, sleepiness, agitation or hallucinations started.
  3. Bring medication lists, alcohol history if relevant, glasses, hearing aids and dentures.
  4. Use short calm sentences; remind the person where they are and that they are safe.
  5. Ask what cause is being treated and what prevention bundle is in place.

Causes checklist

Think in overlapping buckets

Oxygen and perfusion

Hypoxia, hypercapnia, shock, anaemia, myocardial infarction, arrhythmia, pulmonary embolism.

Infection and inflammation

Pneumonia, UTI with true symptoms/signs, sepsis, cellulitis, abdominal source, CNS infection, COVID-like illness.

Metabolic

Hypo/hyperglycemia, sodium, calcium, renal/liver failure, dehydration, acid-base disorder, endocrine crisis.

Neurologic

Stroke, bleed, head injury, seizure, non-convulsive status, tumour, CNS infection, hypertensive encephalopathy.

Medication and toxin

Anticholinergic burden, sedatives, opioids, steroids, drug interactions, renal accumulation, intoxication.

Withdrawal

Alcohol, benzodiazepines, barbiturates, opioids and other substance withdrawal syndromes.

Environment and function

Sleep deprivation, sensory deprivation, immobilization, catheters, restraints, pain, unfamiliar surroundings.

Psychiatric overlap

Depression, mania, psychosis, trauma and catatonia can mimic or compound delirium, but do not exclude medical causes.

Older adult walking with a frame beside a clinician

Recovery

Delirium can fade, but follow-up matters.

Some people recover quickly; others have weeks to months of sleep disturbance, fear, poor concentration or reduced function. Document the episode, deprescribe where possible, screen cognition after recovery, and warn future surgical or hospital teams that delirium risk is higher next time.

Evidence base

Selected reputable references

This educational site summarizes guideline and review evidence; it is not a substitute for local clinical protocols, emergency assessment or specialist advice.

NICE CG103: Delirium prevention, diagnosis and management. Published 2010; updated Jan 18, 2023. Delirium.org.au: Australian delirium information, resources and clinical education links. Menzies AIMhi delirium resource: information sheet discussing delirium for health workforce audiences. Menzies AIMhi Delirium PDF: pictorial information sheet / brochure for delirium education. American Delirium Society: U.S. professional society, education, meetings and delirium resources. Alasdair MacLullich LinkedIn profile: delirium researcher, 4AT and European Delirium Association profile. Rudolph J. In Memoriam: James "Jim" Rudolph. Delirium. Published online Apr 29, 2026. Brown University School of Public Health notice on the passing of Dr. James Rudolph, Mar 30, 2026. American Psychiatric Association Practice Guideline for Prevention and Treatment of Delirium. Published Sep 2025; page updated Jun 18, 2026. NICE CG103 treating delirium recommendations: identify causes, communicate, de-escalate and short-term haloperidol only when needed. American Geriatrics Society postoperative delirium guideline: treatment, nonpharmacologic care and medication cautions. Official 4AT user guide: scoring, interpretation and use in untestable patients. QUT delirium education: CAM short diagnostic algorithm. Pun and Boehm. Implementing delirium screening in the ICU: CAM-ICU and ICDSC overview. Validation of a nurse-based delirium-screening tool for hospitalized patients: Nu-DESC performance and thresholds. Systematic review: multicomponent interventions to prevent delirium in older patients with hip fracture. Smith et al. Risk factors for postoperative delirium after hip fracture surgery: systematic review and meta-analysis. Yajima et al. Predictive ability of preoperative Mini-Cog for postoperative delirium: systematic review and meta-analysis. American College of Surgeons geriatric surgery resources, including NSQIP/AGS preoperative and perioperative guidelines. American Delirium Society Family CAM resources for family caregiver delirium detection. FAM-CAM convergent validity study: family caregiver screening for delirium in older adults with cognitive impairment. Greater Manchester Community Delirium Toolkit for community and family delirium identification and management. INTERACT II: tools to identify changes early and reduce avoidable nursing-home transfers to hospital. CMS Initiative to Reduce Avoidable Hospitalizations among Nursing Facility Residents. Oh ES, Fong TG, Hshieh TT, Inouye SK. Delirium in Older Persons: Advances in Diagnosis and Treatment. JAMA. 2017. Wilson JE, Mart MF, Cunningham C, et al. Delirium. Nature Reviews Disease Primers. 2020. Inouye SK. Delirium in Older Persons. New England Journal of Medicine. 2006. American Geriatrics Society guideline for postoperative delirium in older adults. Journal of the American Geriatrics Society. 2015. SCCM PADIS ICU Guidelines. Critical Care Medicine. 2018. American Geriatrics Society 2023 updated Beers Criteria for potentially inappropriate medication use in older adults. American Family Physician: Delirium in Older Persons: Prevention, Evaluation, and Management. 2023.